6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids

A study from India compared the inhibitory effect of 6-shogaol, the pungent component in Ginger root (yes, the one we have at the supermarket) to Taxol, a known chemo, on Breast Cancer cells, as well as Breast Cancer Stem cells (CSCs). Results showed that 6-shogaol was more potent than Taxol and in addition inhibited the stem cells, which pose a serious obstacle to cancer therapy as they can be responsible for poor prognosis and tumor relapse. Furthermore, 6-shogal was not toxic to non-cancerous cells, even at high doses. Previously, Turmeric and Green Tea have been shown to be efficacious against certain types of cancer cells.

Source: Vasudevan RA et al. "6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death" 2015. PLoS ONE 10(9): e0137614. doi:10.1371/journal.pone.0137614 http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0137614#sec025

This post is also available in: Hebrew

No Comments Yet.

Leave a comment

You must be Logged in to post a comment.

%d bloggers like this: